VitaMedica’s Clear Skin Formula has been recommended for 20 years by medical skin care professionals for their patients with mild to moderate non-cystic acne, aged 12 years or older.
Our Clear Skin + Probiotics Bundle is formulated with vitamins, minerals, botanicals, and probiotics to address skin health internally and promote a clear complexion.†
Non-cystic acne medications can have potent activity but may have significant side-effects. Go au natural by enhancing the body’s natural systems for repairing, cleansing, and normal healing.†
- Nutrients like vitamin A, zinc, and vitamin E are significantly lower in the people with acne.
- A combination of vitamin A plus Betatene®, a natural mixed carotenoid blend, reduces sebum production, stimulates skin cell growth to support healing, helps smooth and even skin tone, and has a normalizing effect on skin.†
- Zinc, a trace mineral essential for protein synthesis and collagen formation, supports wound healing, immune system activity, inflammatory control and tissue regeneration. Evidence suggests zinc has antibacterial and anti-inflammatory effects and that it may decrease sebum production. Zinc is also involved in the proper metabolism of testosterone, the principal androgen involved in acne.†
- Vitamin C is an antioxidant and essential component for the development of collagen, the main protein that provides structural support to the skin.†
- The oxidation of sebum, damaged by bacterial growth, may be responsible for the inflammatory aspects of acne. Vitamin E is a fat-soluble antioxidant that prevents the oxidation of fats in the body, including sebum.†
- Chromium, another trace mineral, promotes a healthy glucose response, healthy sugar metabolism, addresses hormonal imbalance and compromised nutrient utilization. Helps to counter the acne-inducing effects of a high-glycemic diet including abnormal skin cell shedding.†
- Bromelain, an enzyme extracted from pineapple, and the trace mineral selenium bring anti-inflammatory activity that helps soothe irritated skin.†
- Burdock, Oregon Grape, dandelion, and yellow dock contain herbal compounds known for their skin and blood cleansing properties to help remove toxins from the skin.†
- Broad-spectrum probiotic formula favorably alters intestinal balance to promote skin health, healthy digestion & regularity, and immune system function.†
- A healthy skin microbiome supports the skin’s barrier function. Probiotics repopulate the gut with microorganisms that tame inflammation and positively influence the skin microbiome by promoting bacterial balance, improving GI function, removing gut toxins, and quelling inflammation.
- Featuring 8 different species of beneficial flora including strains of Lactobacillus, Bifidobacterium and Streptococcus.
- FOS prebiotic fiber nourishes beneficial bacteria and provides optimal synbiotic support.†
- Delivers acid-resistant microflora directly to the intestine, bypassing the harsh acidic conditions of the stomach.
- Cellulose capsules ideal for vegans and vegetarians.
- Does not require refrigeration.
Taking Clear Skin + Probiotics Bundle is a great first step in dealing with problem skin. To learn more about the dietary and lifestyle steps you can take to get naturally, healthy-looking skin, check out our Acne Vitamins page
Nutrition & Ingredients
Betatene® is a registered trademark of COGNIS IP MANAGEMENT GMBH.
• The current standard of treatment for acne includes antibiotics, vitamin A derivatives and hormonal drugs; these drugs are useful in acne management but can induce a wide array of adverse effects. i
• The fat-soluble vitamin A and the water-soluble vitamin C are the predominant vitamins at work in the wound-healing process. ii
• A 2010 study found that in patients with mild to moderate facial acne, in 80% of those taking a zinc complex with antioxidant supplement had a significant reduction of acne. The treatment was efficacious and well tolerated. iii
• A 2018 review of 31 clinical studies found that zinc is a promising alternative to other acne treatments owing to its low cost, efficacy, lack of systemic side-effects and well-established safety profile. iv
• The inflammatory progression of acne produces free-radicals. It has been suggested that oxidative stress may be implicated in the origin of acne and that drugs with antioxidant effects (or antioxidant supplements) may be valuable adjuvants in acne treatment. v
• Zinc is a mineral that is essential for the proper development and functioning of human skin. Studies conducted in the 1970s showed that at high dosages, zinc was effective in the treatment in severe and inflammatory acne. vi
• Several studies have shown that low stomach acid is a common finding in patients who have acne. This suggests that the traditional use of bitter herbs, which act by stimulating digestive function, including acid secretion, may be useful and important for correcting acne vulgaris. Herbs with antimicrobial, inflammation- modulating, anticomedogenic, and, in certain cases, hormone-balancing actions are also useful for treating acne. vii
• A 1996 review of the literature found that bromelain is a useful therapeutic compound with anti-inflammatory action. viii
• The use of antibiotics for acne has been questioned owing to resistance concerns, especially since they are used for long periods at low doses. ix
• Certain P. acne strains were highly associated with acne, and other strains were enriched in healthy skin. x
i Leyden, JJ. Therapy for Acne Vulgaris. N Engl J Med. 1997 Apr 17;336(16):1156-62.
ii Arnold, M. and Barbaul, A. Nutrition and Wound Healing. Plas. Reconstr. Surg. 2006 June; 42S-58S.
iii Sardana K, Garg VK. An observational study of methionine‐bound zinc with antioxidants for mild to moderate acne vulgaris. Dermatol Ther. 2010 Jul-Aug;23(4):411-8.
iv Cervantes, J. The role of zinc in the treatment of acne: A review of the literature. Volume31, January/February 2018, pp. 1-17.
v Bowe WP. Diet and Acne. JAAD. July 2010. Volume 63, Issue 1, Pages 124–141.
vi Bowe WP. Diet and Acne. JAAD. July 2010. Volume 63, Issue 1, Pages 124–141.
vii Yarnell, E, Abascal K. Herbal Medicine for Acne Vulgaris. Alternative and Complementary Therapies. Vol. 12, No. 6.
viii Reference: Kelly, S. Gregory. Bromelain – A Literature Review and Discussion of its Therapeutic Applications. Alt Med Review. 1: 4, 243-257, 1996.
ix Williams HC, Dellavalle RP, Garner S. Acne vulgaris. Lancet. 2012 Jan 28;379(9813):361-72.
x Fitz-Gibbon S. Propionibacterium acnes strain populations in the human skin microbiome associated with acne. J Invest Dermatol. 2013 Sep;133(9):2152-60.
How to Use
Clear Skin Formula
Directions: As a dietary supplement, take two capsules with food. Each individual is unique and nutritional requirements may vary.
Daily Balance Probiotic-8
Directions: As a dietary supplement, take two capsules daily between meals or on an empty stomach. Each individual is unique and nutritional requirements may vary.
WARNINGS: Do not take if safety seal on bottle is broken. KEEP OUT OF REACH OF CHILDREN. If you are diabetic, pregnant or breast-feeding, seek advice of your physician before using this product.
CLEAR SKIN FORMULA contains Vitamin A. If you are presently taking any vitamin A containing medications for the treatment of acne, please refrain from taking CLEAR SKIN FORMULA until the end of the treatment cycle.
Not manufactured with wheat, soy, egg, fish, shellfish, peanuts or tree nut ingredients. Produced in a GMP-certified facility that processes other ingredients containing these allergens.
Storage: Store in a cool, dark place.
1. What is the primary benefit of using Clear Skin + Probiotics Bundle?
Clear Skin + Probiotics Bundle is formulated with nutrients that promote skin health, reduce sebum production, enhance inflammatory control, and have antiseptic properties, plus probiotics that replenish the microbiome and maintain microbial balance in the skin.
2. What makes VitaMedica’s Clear Skin + Probiotics Bundle unique?
Clear Skin + Probiotics Bundle is designed to address each factor contributing to the formation of acne. Although an inflammatory skin condition such as acne can strike at any age, its onset is most often related to a change in hormones and bacterial imbalance in the microbiome, which explains why certain populations including teens and pregnant women are particularly prone to acne breakouts. Excess androgen production can cause the sebaceous glands to excrete more sebum, which in turn clogs the follicle and allows a bacterium called P. acnes to overpopulate. The result is inflammation and acne blemishes in the form of whiteheads or blackheads, depending on whether the pore is closed or open.
Clear Skin Formula contains zinc to help regulate testosterone – the primary hormone involved in sebum production. Vitamin A (carotenoid and palmitate form) promotes normal epithelization of the skin cells and reduces sebum production. MSM (Methylsulfonylmethane) acts as a natural anti-microbial. Selenium and bromelain are included naturally reduce the inflammation. Healing herbs help to detoxify and cleanse the blood and skin. Finally, an ideal blend of probiotics plus prebiotic FOS replenishes the microbiome with health-promoting microorganisms, bringing microbial balance to the skin via the gut-brain-skin axis.
3. Can diet affect acne and other skin problems?
Yes. Although hotly debated within the medical community in the past, a growing consensus based on increasing research-based evidence agrees that in addition to genetics, hormones, exercise, and stress, diet (and the quality of gut bacteria it provides) can be a major factor in many skin conditions including acne. The skin is often referred to as the third kidney for its role in removing toxins from the body, and studies have shown that some patients with acne have intestinal toxemia (toxins build up in the intestine due to poor nutrition) that may be contributing to their condition. Other studies have found that patients with psoriasis and eczema improved their condition with alpha-linolenic (Omega-3) essential fatty acid supplementation. It simply makes sense that the quality of nutrients consumed will affect the quality of an individual’s skin.
4. Who should use Clear Skin + Probiotics Bundle?
Clear Skin + Probiotics Bundle is indicated for patients with non-cystic acne. The product is suitable for patients 12 years or older. This nutraceutical is ideal for individuals who do not eat a well-balanced diet on a consistent basis. Because of the poor dietary habits of people who are 15-40 years of age, Clear Skin + Probiotics Bundle is particularly well-suited for patients in this age group.
5. Who should not use Clear Skin + Probiotics Bundle?
Nutritional supplements have an excellent safety track record. However, certain individuals should seek the advice of their doctor before beginning any nutritional supplement program particularly diabetics, pregnant or lactating women. Clear Skin Formula contains vitamin A (palmitate). If you are presently taking a vitamin A containing medication for the treatment of acne, refrain from taking Clear Skin Formula until 6 months after the end of the treatment cycle. Please refer to the Directions section for more information on precautions and contraindications.
6. How do prescription and over the counter (OTC) medications for acne differ from nutritional supplements?
Prescription and OTC acne medications can have powerful activity – with significant side effects. Natural medicines tend to be milder, safer, and far less likely to cause negative reactions. Many topical treatments for the care of acne and inflammatory disorders of the skin have been shown to be effective, and yet are limited by only targeting the outermost layers of the skin. The skin is incredibly good at preventing potential pathogens from entering the body, which also means it is extremely difficult for the active ingredients in topical products to penetrate the deeper layers of the dermis. Therefore, it makes sense to use a bi-directional approach that addresses both the external and internal causes behind the formation of acne blemishes by coupling high-quality topicals with a wholesome diet and supplements.
7. Clear Skin + Probiotics Bundle is formulated with vitamin A. Why is vitamin A important for acne?
Vitamin A plays a role in skin health because it is needed for the maintenance and repair of epithelial tissue, which forms the skin and mucous membranes. Vitamin A stimulates the growth of the base layer of the skin cells. It also helps cells to differentiate normally and gives them their structural integrity. Vitamin A plays such an important role in dermal health that many topical acne medications are derivatives of this vitamin.
8. Clear Skin + Probiotics Bundle is formulated with vitamin C. Why is vitamin C important for acne?
Vitamin C is a water-soluble vitamin that is essential for the development of collagen, the most abundant protein in the body. Collagen provides structural support to the skin. Vitamin C is also a potent antioxidant that works in concert with vitamin E to protect cells from free-radical damage. Research published in 2006 found that reactive oxygen species can damage skin and increase inflammation and scarring related to acne. Ingesting or applying vitamin C may help ward off these damaging free-radicals.
9. Clear Skin + Probiotics Bundle is formulated with vitamin E. Why is vitamin E important for acne?
Vitamin E is a fat-soluble antioxidant that prevents the oxidation of fats in the body. The oxidation of sebum, damaged by bacterial growth, may be responsible for the inflammatory aspects of acne. Vitamin E prevents irritating oxidation of sebum. Vitamin E is important for the proper functioning of vitamin A, a key acne vitamin.
10. Clear Skin + Probiotics Bundle is formulated with vitamin A from palmitate and a carotenoid source (Betatene®). Why are both forms provided?
Both forms are provided to ensure safety and efficacy. As a fat-soluble nutrient, vitamin A is stored in the liver and fatty tissue of the body. This creates a concern if too much of this vitamin is taken over time (e.g. upwards of 50,000 IUs daily for over 3 months). Clear Skin Formula is formulated with a modest dose of vitamin A (12,500 IUs total), provided in both the palmitate (7,500 IUs) and carotenoid (5,000 IUs) form. While palmitate is directly utilized as vitamin A, carotenoids must convert into vitamin A to be used by the body. The conversion process for the few carotenoids that have pro-vitamin A activity is not very efficient. For example, six to twelve times more beta-carotene is required to convert into one retinol unit of vitamin A activity. That is why toxicity is not an issue with a carotenoid source. By providing both preformed vitamin A (palmitate) and a natural, mixed blend of carotenoids (Betatene®), Clear Skin Formula delivers an efficacious, yet safe dose of vitamin A to support healthy skin function.
11. Clear Skin + Probiotics Bundle is formulated with zinc. Why is zinc important for acne?
Zinc is a trace mineral that is essential for protein synthesis and collagen formation. Zinc is involved in the proper metabolism of testosterone, the principal hormone involved in the genesis of acne through its role in sebum production. The mineral is also involved in vitamin A function, wound healing, immune system activity, inflammatory control, and tissue regeneration.
12. Clear Skin + Probiotics Bundle is formulated with selenium. Why is selenium important for acne?
Selenium is an antioxidant that works to protect other antioxidants such as vitamin E and is important in keeping tissues elastic. Research has also shown that a deficiency in selenium may play a role in inflammatory conditions such as eczema and psoriasis. Selenium functions in glutathione peroxidase, an enzyme which is very important in preventing the inflammation of acne.
13. Clear Skin + Probiotics Bundle is formulated with chromium. Why is chromium important for acne?
Chromium is a trace mineral that works with insulin in the metabolism of sugar and is needed for energy. Chromium also improves glucose tolerance and enhances insulin sensitivity. This is important for some acne patients who do not metabolize sugar properly.
14. I noticed in the Supplement Facts panel the word chelate after each mineral. What does chelate mean?
In general, our bodies absorb vitamins without much difficulty, but minerals are not absorbed as well. Chelation is a process that combines a mineral with an amino acid. This process of chelation enhances the absorption of minerals by fooling the body into thinking it is absorbing the amino acid attached to the mineral. The mineral is pulled into the body along with the amino acid, ensuring its absorption. Chelated minerals are more expensive because of the extra step required to attach the amino acid to the mineral. However, this expense is worth it due to the improved absorption.
15. Clear Skin + Probiotics Bundle is formulated with bromelain. Why is bromelain important for acne?
Bromelain is a proteolytic enzyme (digests protein) that is extracted from the stem of the pineapple. Bromelain contains compounds that support a healthy inflammatory response.
16. Clear Skin + Probiotics Bundle is formulated with MSM. Why is MSM important for acne?
MSM or methylsulfonylmethane is a natural form of organic sulfur that is necessary for collagen synthesis. MSM is critical in building the sulfur amino acids methionine and cysteine. MSM is also a natural antiseptic that works as an antimicrobial. MSM enhances tissue pliability and encourages the repair of damaged skin. By keeping skin cells soft, MSM allows the skin to detoxify. The combination of MSM and vitamin C works faster to heal wounds.
17. Clear Skin + Probiotics Bundle is formulated with several herbs. Why are these herbs included and what is their importance for acne?
The skin has several functions including temperature regulation, protection of the underlying tissues, fat storage, and immunity. Along with the kidneys, the skin also plays a role in eliminating toxins from the body. In fact, the skin is often referred to as the “third kidney”. The elimination of toxins through the skin can promote the development of acne. Herbs like burdock, dandelion, yellow dock, and Oregon grape, are included in Clear Skin Formula for their potent cleansing properties of the skin and blood.
18. What other VitaMedica products may be beneficial to support a clear-complexion?
Healthy-looking skin that is clear of acne reflects a health-promoting diet rich in fruits, vegetables, as well as high-quality protein and fat sources. VitaMedica’s nutraceuticals are designed to help cover any nutrient gaps that may remain, and target specific health objectives. Our Clear Skin Bundles provide nutrients to banish blemishes from the inside out and promote a clear complexion. Anti-Aging Formula, our most popular wellness product, includes our high-quality Multi-Vitamin & Mineral plus our Phyto-5 Phytonutrient Complex and organic flax seed oil in 30 convenient daily packs.
Have additional questions?
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